Amlodipine combined with terazosin reduces postvoid residual and the risk of acute urinary retention / 中华男科学杂志
National Journal of Andrology
;
(12): 441-444, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-292355
ABSTRACT
<p><b>OBJECTIVE</b>This prospective randomized double-blinded clinical trial was designed to explore the effects of amlodipine and the combination of amlodipine with terazosin in improving postvoid residual (PVR) in patients with lower urinary tract symptoms (LUTS) and concomitant hypertension.</p><p><b>METHODS</b>We randomly divided 360 LUTS patients with concomitant hypertension into a 5 mg amlodipine group, a 2 mg terazosin group and a 5 mg amlodipine plus 2 mg terazosin group, and measured PVR at the baseline and 4 weeks after the treatment.</p><p><b>RESULTS</b>For male patients with LUTS associate with hypertension, all of amlodipine (APVR = 6.8) , terazosin (APVR = 7. 6), and combination group (APVR = 8.8) can significant reduced the PVR (P < . 0.1), but no significant difference was found among three groups.</p><p><b>CONCLUSION</b>Amlodipine alone or combined with terazosin can improve the PVR of the LUTS patient effectively, but had no significant difference compared with terazosin.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Hiperplasia Prostática
/
Urodinâmica
/
Prazosina
/
Método Duplo-Cego
/
Estudos Prospectivos
/
Retenção Urinária
/
Resultado do Tratamento
/
Anlodipino
/
Antagonistas Adrenérgicos alfa
/
Usos Terapêuticos
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo de etiologia
/
Estudo observacional
/
Fatores de risco
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2009
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS