Expression of estrogen receptor beta in benign prostatic hyperplasia complicated by chronic prostatitis / 中华男科学杂志
National Journal of Andrology
;
(12): 314-317, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-292380
ABSTRACT
<p><b>OBJECTIVE</b>To observe the expression of estrogen receptor-beta (ERbeta) in benign prostatic hyperplasia (BPH) complicated by chronic prostatitis, and to evaluate the correlation of chronic prostatitis with ERbeta expression.</p><p><b>METHODS</b>Histological sections of prostate tissues were obtained from 60 BPH patients complicated by chronic prostatitis and divided into Group 1 (Grade 1), 2 (Grade 2) and 3 (Grade 3) according to the scores on the inflammation of the prostate tissues using the four-point scale designed by Irani et al. The expression of ERbeta was determined by the immunohistochemical method.</p><p><b>RESULTS</b>There were 24 cases (40%) in Group 1, 21 (35%) in Group 2 and 15 (25%) in Group 3, with no statistically significant differences in age and prostate volume among the three groups (P > 0.05). The expression of ERbeta was significantly decreased in Groups 2 and 3 as compared with Group 1 (P < 0.01).</p><p><b>CONCLUSION</b>The expression of ERbeta is reduced with increased scores on the inflammation of the prostate tissues in BPH patients, and the decreased ERbeta expression may be associated with the inflammatory stimulation of prostatitis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Hiperplasia Prostática
/
Prostatite
/
Doença Crônica
/
Receptor beta de Estrogênio
/
Metabolismo
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2009
Tipo de documento:
Artigo
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