AZF microdeletions are not related with recurrent spontaneous abortion / 中华男科学杂志
National Journal of Andrology
;
(12): 1099-1102, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-292446
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between azoospermia factor (AZF) microdeletions of the Y-chromosome and recurrent spontaneous abortion.</p><p><b>METHODS</b>We collected 26 chorionic villus samples from abortive male embryos and 51 blood samples from the husbands whose wives had recurrent spontaneous abortion, extracted genomic DNA from the samples and detected 12 STSs in the AZFa, AZFb and AZFc regions of Yq11.2 by amplification multiplex PCR.</p><p><b>RESULT</b>AZF microdeletions were found neither in the chorionic villus samples nor in the blood samples.</p><p><b>CONCLUSION</b>There is no relationship between AZF microdeletions and recurrent spontaneous abortion.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Aborto Espontâneo
/
Aborto Habitual
/
Reação em Cadeia da Polimerase
/
Deleção Cromossômica
/
Proteínas de Plasma Seminal
/
Cromossomos Humanos Y
/
Loci Gênicos
/
Genética
/
Métodos
Limite:
Feminino
/
Humanos
/
Masculino
/
Gravidez
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2008
Tipo de documento:
Artigo
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