Study on adverse drug reaction in Yuixngcao injection literatures / 中国中药杂志

ABSTRACT

Yuxingcao injection was suspended by China State Food and Drug Administration in 2006 for its severe adverse reaction in clinical practice. Althoug there are many real factors resulted in Yuxingcao injection's adverse reaction, some confounding factors should not be ignored. This study searched different kinds of related literatures and found out irregularity in defining dosage, disuses courses, indications and administration approach, which were the potential factors that caused the reported adverse drug reaction for Yuxingcao injection. And 97.8% adverse drug reaction in Yuxingcao injection happened 30 minutes after patients received administion, hence, observing patients'reaction in the first 30 minutes should be very important to prevent severe adverse drug reaction.