Protective effects of Cleistocalyx operculatus on lipid peroxidation and trauma of neuronal cells / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 964-966, 2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-293677
ABSTRACT
<p><b>OBJECTIVE</b>To observe the protective effects of Cleistocalyx operculatus on lipid peroxidation in rat liver microsomes and on the trauma of PC12 cells induced by H2O2.</p><p><b>METHOD</b>The mouse liver homogenate lipid peroxidation assay and PC12 Cell culture and Cell viability (MTT assay) were applied.</p><p><b>RESULT</b>Cleistocalyx operculatus showed strong protective effects on lipid peroxidation in rat liver microsomes in a dose-dependent manner and exhibited potent protective effects on the trauma of PC12 cells induced by H2O2 (200 micromol x L(-1)) when the concentration reached 1.00 g x L(-1).</p><p><b>CONCLUSION</b>Cleistocalyx operculatus may be used as antioxidant to prevent or delay the pathogenesis of neural cell diseases.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Microssomos Hepáticos
/
Medicamentos de Ervas Chinesas
/
Peroxidação de Lipídeos
/
Química
/
Células PC12
/
Fármacos Neuroprotetores
/
Citoproteção
/
Myrtaceae
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2003
Tipo de documento:
Artigo
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