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Evaluation on the highly active anti-retroviral therapy in 181 AIDS patients / 中华流行病学杂志
Chinese Journal of Epidemiology ; (12): 704-707, 2007.
Artigo em Chinês | WPRIM | ID: wpr-294252
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical effect under highly active anti-retroviral therapy (HAART) in AIDS patients and for improving the curative effect and prognosis.</p><p><b>METHODS</b>Epidemiological method was used from five aspects to describe the post-treatment clinical symptoms of 181 AIDS patients in Suizhou, and to evaluate the change of virus load and immune function of 79 AIDS patients. Data was doubly recorded by Epi Data and database was set up by SPSS 13.0 for analysis.</p><p><b>RESULTS</b>The effective powers of anomal-fever, cough, diarrhoea, lymphadenectasis, weight drop, erythra, mycotic infection were 81.39%, 85.00%, 84.62%, 81.89%, 82.86%, 66.07% and 45.45% respectively. CD4+ T lymphocyte count rose obviously after treatment, with an averag of 276 x 10(6) cells/ml (65 x 10(6)-824 x 10(6) cells/ml), an 129 x 10(6) cells/ml increase in three months and was 294 x 10(6) cells/ml (102 x 10(6)-750 x 10(6) cells/ml) in six months. The count change of CD4+ T lymphocyte between 3 months and 6 months did not show sigificant difference. The number of deaths among drug withdrawals was 14, with a case fatality rate as 29.79%; while the number of deaths among non-drug withdrawals was 3, with the case fatality rate as 2.24%.</p><p><b>CONCLUSION</b>Results through this study showed that HAART could obviously improve the clinical symptom of AIDS patients, and to increase the number of virus load. Improving the compliance could also reduce the case fatality rate.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Virologia / Linfócitos T CD4-Positivos / Estudos Prospectivos / Inquéritos e Questionários / Síndrome da Imunodeficiência Adquirida / Resultado do Tratamento / Terapia Antirretroviral de Alta Atividade / Tratamento Farmacológico / Alergia e Imunologia Tipo de estudo: Estudo observacional Limite: Adulto / Feminino / Humanos / Masculino Idioma: Chinês Revista: Chinese Journal of Epidemiology Ano de publicação: 2007 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Virologia / Linfócitos T CD4-Positivos / Estudos Prospectivos / Inquéritos e Questionários / Síndrome da Imunodeficiência Adquirida / Resultado do Tratamento / Terapia Antirretroviral de Alta Atividade / Tratamento Farmacológico / Alergia e Imunologia Tipo de estudo: Estudo observacional Limite: Adulto / Feminino / Humanos / Masculino Idioma: Chinês Revista: Chinese Journal of Epidemiology Ano de publicação: 2007 Tipo de documento: Artigo