Research on prerequisite for using bovine hemoglobin modified by polyethylene glycol as a red blood cell substitute / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 815-819, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-294562
ABSTRACT
This paper aims to raise concerns about the modification of bovine hemoglobin with the use of SC-mPEG as modifying reagent. The yield rates of SC-mPEG-BHB under dissimilar conditions are studied, and more important, a series of methods used to characterize the SC-mPEG-BHB mixtures are built. The best reactive system has been confirmed, i.e., at 4 degrees C, pH9; SC-mPEG and BHB are mixed according to the proportion of 601 and be submitted to reaction for 2 h.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Polietilenoglicóis
/
Substitutos Sanguíneos
/
Hemoglobinas
/
Química
/
Classificação
/
Concentração de Íons de Hidrogênio
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2009
Tipo de documento:
Artigo
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