Preparation of novel bioactive PCL bone tissue engineering scaffold / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 550-565, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-294619
ABSTRACT
In the present study, porous PCL (poly (epsilon-caprolactone)) scaffolds were prepared through a melted extrusion manufacturing (MEM) machine, and carboxylate groups were formed on the surfaces of specimen by hydrolyzation with NaOH aqueous solutions. Apatite precursor was introduced on the surfaces of specimens with CaCl2 and K2 HPO4 under vacuum condition, and mineralization study was applied to these specimens. The results showed that the hydrophilicity of PCL surface was improved with the introduction of carboxylate groups, and the contact angle of surface was decreased to 26.52 degrees. A dense and uniform bone-like layer was confirmed to be formed on the surface of Ca-P treated specimens after mineralizing for less than 24 h in SBF by SEM and EDAX.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Poliésteres
/
Materiais Biocompatíveis
/
Regeneração Óssea
/
Química
/
Engenharia Tecidual
/
Regeneração Tecidual Guiada
/
Alicerces Teciduais
/
Métodos
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2009
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS