Diagnosis and management of scrotal Paget's disease: report of 23 cases / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the clinical manifestation, management, recurrence factors and prognosis of scrotal Paget's disease.</p><p><b>METHODS</b>We retrospectively analyzed the clinical and pathological data of 23 cases of scrotal Paget's disease diagnosed and treated in our hospital from 1996 to 2008.</p><p><b>RESULTS</b>The disease was confined to one side of the scrotum in 15, and involved the whole scrotum and penis in 8 of the cases. Three patients showed enlarged inguinal lymph nodes in the same side, and 2 in both sides. All the cases were confirmed by biopsy and treated by surgery. Post-operative follow-up was conducted for 2-68 months, which revealed 5 cases of local recurrence and 1 case of death for systemic metastasis.</p><p><b>CONCLUSION</b>Biopsy is proved to be important for the early diagnosis of scrotal Paget's disease, and extended excision of local lesion is a preferred management.</p>