Absorption and isolation of macroporous resin for five salvianolic acids from Salviae mitiorrhizae / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the adsorption of the macroporous resin for the five salvianolic acids (danshen su, rosmarinic acid, protocate chualdehyde, salvianolic acid B, salvianolic acid A, extracted from Salviae mitiorrhizae.</p><p><b>METHOD</b>The five salvianolic acids were employed as an index, and the change of them in the static and dynamic absorbent was detected by HPLC, respectively.</p><p><b>RESULT</b>HP20 resin was a suitable marcoporous resin to purify salvianolic acids. The dynamic adsorption capacity of rosmarinic acid, salvianolic acid B and salvianolic acid A was 30.506 mg x g(-1) (dry resin), 36.996 mg x g(-1), (dry resin), 43.85 mg x g(-1) (dry resin) respectively.</p><p><b>CONCLUSION</b>It is not suitable that danshensu and protocate chualdehyde are the evaluation indexes for using 8 macroporous resins to purify salvianolic acids.</p>