Cox regression analysis on influencing factors of coronary heart disease among people over 40 years of age / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the affecting factors on coronary heart disease among people over 40 years of age in Guangxi area, China.</p><p><b>METHODS</b>Baseline data was gathered through the Third National Blood Pressure Survey in 1991 in China. A total number of 11 818 adults over 40 years old had been studied in Guangxi province. Data of morbidity and mortality of coronary heart disease was obtained.</p><p><b>RESULTS</b>Cardiovascular events were related to systolic blood pressure, diastolic blood pressure, pulse pressure, smoking, BMI regardless of their myocardial infarct (MI) history. Cox regression analysis showed that the relative risk for cardiovascular events increased by 21 [95% confidence interval (CI) 9.06-48.44] times for those people having MI history. When pulse pressure, systolic blood pressure, diastolic blood pressure increased by every 10 mm Hg, the relative risk for cardiovascular events increased by 1.29 (95% CI 1.11-1.49), 1.18 (95% CI 1.02-1.22), 1.13 (95% CI 1.05-1.28) respectively. There was 1.23 (95% Cl 1.05-1.45) times higher in smoker than non-smoker on relative risk for cardiovascular events. When BMI increasing 1, the relative risk for cardiovascular events would increase 1.03 (95% CI 1.01-1 .05) times.</p><p><b>CONCLUSION</b>Hypertension, smoking, increase of BMI were the risk factors of coronary heart disease among people who were over 40 years of age.</p>