A study on the relationship between genetic and environmental factors of type 2 diabetes mellitus in humans / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 191-194, 2002.
Artigo
em Inglês
| WPRIM
| ID: wpr-295773
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between the inheritable factor and environmental factors of type 2 diabetes mellitus in humans.</p><p><b>METHODS</b>A case-control study based on 154 type 2 diabetes mellitus and 130 healthy controls was carried out in Jiangsu Province in 1997.</p><p><b>RESULTS</b>The age, family history of diabetes mellitus, hypertension history, high waist/hip ratio (WHR), high systolic blood pressure, huge fetus history, and the genotype of beta(3)-adrenergic receptor (beta(3)-AR) were the risk factors of type 2 diabetes mellitus; while occupational physical activity was protective factor of type 2 diabetes mellitus. The risk for diabetes mellitus distinctly increased while genetic factor and obesity, beta(3)-AR mutation were coexisting.</p><p><b>CONCLUSION</b>Type 2 diabetes mellitus is caused by the effect of both genetic and environmental factors.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Estudos de Casos e Controles
/
Modelos Logísticos
/
China
/
Epidemiologia
/
Análise Multivariada
/
Fatores de Risco
/
Diabetes Mellitus Tipo 2
/
Meio Ambiente
/
Genética
/
Obesidade
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Chinese Journal of Preventive Medicine
Ano de publicação:
2002
Tipo de documento:
Artigo
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