Research Progress in the Core Proteins of the Classical Swine Fever Virus / 病毒学报
Chinese Journal of Virology
;
(6): 579-584, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-296244
ABSTRACT
The core protein (CP) of the classical swine fever virus (CSFV) is one of its structural proteins. Apart from forming the nucleocapsid to protect internal viral genomic RNA, this protein is involved in transcriptional regulation. Also, during viral infection, the CP is involved in interactions with many host proteins. In this review, we combine study of this protein with its disorders, structural/functional characteristics, as well as its interactions with the non-structural proteins NS3, NS5B and host proteins such as SUMO-1, UBC9, OS9 and IQGAP1. We also summarize the important part played by the CP in CSFV pathogenicity, virulence and replication of genomic RNA. We also provide guidelines for further studies in the CP of the CSFV.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Suínos
/
Virologia
/
Virulência
/
Química
/
Proteínas do Core Viral
/
Genoma Viral
/
Genética
/
Peste Suína Clássica
/
Vírus da Febre Suína Clássica
/
Metabolismo
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Virology
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS