Renal Tubular Acidosis in Patients with Primary Sjögren's Syndrome
Electrolytes & Blood Pressure
;
: 17-22, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-29648
ABSTRACT
Primary Sjögren's syndrome (pSS) is characterized by lymphocytic infiltration of the exocrine glands resulting in decreased saliva and tear production. It uncommonly involves the kidneys in various forms, including tubulointerstitial nephritis, renal tubular acidosis, Fanconi syndrome, and rarely glomerulonephritis. Its clinical symptoms include muscle weakness, periodic paralysis, and bone pain due to metabolic acidosis and electrolyte imbalance. Herein, we describe the cases of two women with pSS whose presenting symptoms involve the kidneys. They had hypokalemia and normal anion gap metabolic acidosis due to distal renal tubular acidosis and positive anti-SS-A and anti-SS-B autoantibodies. Since one of them experienced femoral fracture due to osteomalacia secondary to renal tubular acidosis, an earlier diagnosis of pSS is important in preventing serious complications.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteomalacia
/
Paralisia
/
Saliva
/
Autoanticorpos
/
Lágrimas
/
Equilíbrio Ácido-Base
/
Acidose
/
Acidose Tubular Renal
/
Debilidade Muscular
/
Diagnóstico
Tipo de estudo:
Estudo diagnóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Electrolytes & Blood Pressure
Ano de publicação:
2017
Tipo de documento:
Artigo
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