Research advances in immunological pathogenesis of immunoglobulin A vasculitis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 837-840, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-297198
ABSTRACT
Immunoglobulin A (IgA) vasculitis is the most common leukocytoclastic small-vessel vasculitis in children and mainly involves the small vessels in the skin, joints, digestive tract, and kidneys. Its pathogenesis is still unclear. Currently, it is believed that environmental factors can cause autoimmune dysfunction and lead to the deposition of IgA-containing immune complexes on the wall of arterioles on the basis of genetic factors. This article reviews the research advances in the role of immune factors in the pathogenesis of IgA vasculitis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Autoanticorpos
/
Vasculite
/
Glicosilação
/
Proteínas do Sistema Complemento
/
Imunoglobulina A
/
Imunoglobulina E
/
Citocinas
/
Alergia e Imunologia
/
Metabolismo
Tipo de estudo:
Estudo de etiologia
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2017
Tipo de documento:
Artigo
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