A clinical study of sertraline and vardenafil in the treatment of premature ejaculation complicated by erectile dysfunction / 中华男科学杂志
National Journal of Andrology
;
(12): 610-612, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-297674
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of sertraline and vardenafil in the treatment of patients with concomitant erectile dysfunction (ED) and premature ejaculation (PE).</p><p><b>METHODS</b>Sixty patients with concomitant ED and PE received at our clinic of andrology were randomly divided into a vardenafil group and a sertraline group. The vardenafil group received flexible doses of vardenafil from 10 mg to 20 mg and the sertraline group 50 mg daily, both for 2 months. The differences in IIEF-5 before and after the treatment were recorded and compared, and the results of ED treatment evaluated. Intravaginal ejaculatory latency time (IELT) was recorded to evaluate the outcome of PE treatment.</p><p><b>RESULTS</b>In the vardenafil group, 24 patients had their ED improved and the efficacy rate was 80%, as compared with 27% in the sertraline group. There was significant difference between the two groups (P < 0.05). Twenty patients had their PE improved in vardenafil group, with an efficacy rate of 67% as compared with 40% in the sertraline group. The difference was significant between the two groups (P < 0.05). In both of the two groups, a significantly higher rate of PE improvement was found in patients with improved ED than in those without. Only mild side effects were recorded, and none withdrew from the treatment.</p><p><b>CONCLUSION</b>To patients with concomitant ED and PE, the key to the treatment is to improve their erectile function, and for this purpose, vardenafil works better than sertraline.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Inibidores de Fosfodiesterase
/
Piperazinas
/
Sulfonas
/
Triazinas
/
Resultado do Tratamento
/
Inibidores Seletivos de Recaptação de Serotonina
/
Sertralina
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Ejaculação
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2007
Tipo de documento:
Artigo
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