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A clinical study of sertraline and vardenafil in the treatment of premature ejaculation complicated by erectile dysfunction / 中华男科学杂志
National Journal of Andrology ; (12): 610-612, 2007.
Artigo em Chinês | WPRIM | ID: wpr-297674
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of sertraline and vardenafil in the treatment of patients with concomitant erectile dysfunction (ED) and premature ejaculation (PE).</p><p><b>METHODS</b>Sixty patients with concomitant ED and PE received at our clinic of andrology were randomly divided into a vardenafil group and a sertraline group. The vardenafil group received flexible doses of vardenafil from 10 mg to 20 mg and the sertraline group 50 mg daily, both for 2 months. The differences in IIEF-5 before and after the treatment were recorded and compared, and the results of ED treatment evaluated. Intravaginal ejaculatory latency time (IELT) was recorded to evaluate the outcome of PE treatment.</p><p><b>RESULTS</b>In the vardenafil group, 24 patients had their ED improved and the efficacy rate was 80%, as compared with 27% in the sertraline group. There was significant difference between the two groups (P < 0.05). Twenty patients had their PE improved in vardenafil group, with an efficacy rate of 67% as compared with 40% in the sertraline group. The difference was significant between the two groups (P < 0.05). In both of the two groups, a significantly higher rate of PE improvement was found in patients with improved ED than in those without. Only mild side effects were recorded, and none withdrew from the treatment.</p><p><b>CONCLUSION</b>To patients with concomitant ED and PE, the key to the treatment is to improve their erectile function, and for this purpose, vardenafil works better than sertraline.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Inibidores de Fosfodiesterase / Piperazinas / Sulfonas / Triazinas / Resultado do Tratamento / Inibidores Seletivos de Recaptação de Serotonina / Sertralina / Usos Terapêuticos / Tratamento Farmacológico / Ejaculação Limite: Adulto / Humanos / Masculino Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2007 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Inibidores de Fosfodiesterase / Piperazinas / Sulfonas / Triazinas / Resultado do Tratamento / Inibidores Seletivos de Recaptação de Serotonina / Sertralina / Usos Terapêuticos / Tratamento Farmacológico / Ejaculação Limite: Adulto / Humanos / Masculino Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2007 Tipo de documento: Artigo