Experience of using three phosphodiesterase type 5 inhibitors in the same period for the treatment of erectile dysfunction / 中华男科学杂志
National Journal of Andrology
;
(12): 226-228, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-297749
ABSTRACT
<p><b>OBJECTIVE</b>To observe and compare the effects and adverse events of the three phosphodiesterase type 5 (PDE-5) inhibitors sildenafil, vardenafil and tadalafil used in the same period for the treatment of erectile dysfunction (ED).</p><p><b>METHODS</b>A total of 311 ED patients were treated with the three PDE-5 inhibitors in the same period, 134 with sildenafil, 109 with vardenafil and 88 with tadalafil, and followed up for 2-11 months. Their effects were compared.</p><p><b>RESULTS</b>Sildenafil produced satisfactory effect in 72 patients (79.12%), vardenafil in 63 (81.81%) and tadalafil in 52 (78.78%), respectively. And the efficacy rates of sildenafil, vardenafil and tadalafil in the treatment of ED with premature ejaculation were 55.56%, 44.44% and 42.3%, respectively. Our study also showed that the young and the newly married preferred vardenafil, the middle-aged chose tadalafil and the older and long-term users tend to take sildenafil. The main reasons for discontinuing the use of the three inhibitors were their high price, incomplete effect and the patients' worry about their adverse action.</p><p><b>CONCLUSION</b>The three PDE-5 inhibitors can produce basically similar effects on ED, all with safety and few mild adverse events.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Inibidores de Fosfodiesterase
/
Seguimentos
/
Tratamento Farmacológico
/
Inibidores da Fosfodiesterase 5
/
Disfunção Erétil
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2007
Tipo de documento:
Artigo
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