Bioinformatic identification and analysis of Schistosoma japonicum adenine phosphoribosyltransferase / 南方医科大学学报
Journal of Southern Medical University
;
(12): 272-275, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-298189
ABSTRACT
<p><b>OBJECTIVE</b>To identify adenine phosphoribosyltransferases in Schistosoma japonicum and analyze their structural features.</p><p><b>METHODS</b>Based on the accessible transcriptome and proteomic data, the S. japonicum adenine phosphoribosyl transferases were identified using bioinformatics approaches including bi-directional homology comparison, domain search and phylogenetic analysis. Homology modeling was also performed to describe the structural features of the proteins.</p><p><b>RESULTS AND CONCLUSION</b>Two homologue sequences of adenine phosphoribosyltransferase were obtained from S. japonicum, and the EST abundance, physico-chemical properties and three-dimensional structures of them were also acquired.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Filogenia
/
Conformação Proteica
/
Schistosoma japonicum
/
Adenina Fosforribosiltransferase
/
Modelos Moleculares
/
Proteínas de Helminto
/
Química
/
Biologia Computacional
/
Genética
/
Isoenzimas
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2007
Tipo de documento:
Artigo
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