Role of dendritic cells in graft rejection after penetrating keratoplasty / 南方医科大学学报
Journal of Southern Medical University
;
(12): 72-74, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-298239
ABSTRACT
<p><b>OBJECTIVE</b>To gain insight into the role of dendritic cells in graft rejection following penetrating keratoplasty by investigating their distribution in rat cornea.</p><p><b>METHODS</b>Orthotopical corneal transplantation was performed and immunohistochemical staining of the whole-mount cornea and the spleen tissue specimen employed to determine the distribution of the dendritic cells in the cornea.</p><p><b>RESULTS</b>Graft rejection occurred in all rats following the transplantation. No OX-62(+) dendritic cells were found in normal cornea but they were present in the epithelium of the cornea graft with allograft rejection.</p><p><b>CONCLUSION</b>OX-62(+) dendritic cells presenting in the rejected cornea may be related to acute graft rejection after penetrating keratoplasty.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Fisiologia
/
Cirurgia Geral
/
Células Dendríticas
/
Ceratoplastia Penetrante
/
Ratos Wistar
/
Ratos Sprague-Dawley
/
Córnea
/
Alergia e Imunologia
/
Rejeição de Enxerto
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2007
Tipo de documento:
Artigo
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