Changes and clinical significance of serum Apelin in patients with severe sepsis and septic shock / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 131-135, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-298728
ABSTRACT
<p><b>OBJECTIVE</b>To explore the changes and clinical significance of serum Apelin in patients with severe sepsis and septic shock.</p><p><b>METHOD</b>We measured the serum level of Apelin with ELISA on different observation days (the 1st, 3rd, and 10th day obtaining the diagnosis) in 26 patients with severe sepsis and septic shock.</p><p><b>RESULTS</b>Serum Apelin significantly increased in sepsis patients when compared with the normal control group (P<0.01); The serum Apelin levels significantly changed among different observation days (P< 0.01). Serum Apelin level was significantly higher in patients with septic shock than those with severe sepsis (P<0.01).</p><p><b>CONCLUSION</b>Serum Apelin level changes in patients with severe sepsis and septic shock, which may provide clues in diagnosis and prognosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Choque Séptico
/
Fatores de Tempo
/
Sangue
/
Ensaio de Imunoadsorção Enzimática
/
Mortalidade
/
Sepse
/
Peptídeos e Proteínas de Sinalização Intercelular
/
Apelina
Tipo de estudo:
Estudo prognóstico
Limite:
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2008
Tipo de documento:
Artigo
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