Potential targets for anti-liver fibrosis / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1365-1371, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-299126
ABSTRACT
Liver fibrosis is a pathological process of the excessive accumulation of extracellular matrix, especially collagen al (I) in liver. Ultimately, hepatic fibrosis leads to cirrhosis or hepatic failure. Liver fibrosis and early cirrhosis can be reversed, thus control of the development of liver fibrosis is very important for preventive treatment of cirrhosis and hepatic failure. This is a review of potential targets for anti-hepatic fibrosis based on plenty of publications, including TGF-β1 and integrin α(v) and so on, aimed at providing novel therapeutic targets in liver fibrosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Colágeno
/
Integrina alfaV
/
Tratamento Farmacológico
/
Fator de Crescimento Transformador beta1
/
Fígado
/
Cirrose Hepática
/
Metabolismo
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2014
Tipo de documento:
Artigo
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