Oncologic Outcome of Sacral Chordoma / 대한골관절종양학회지
The Journal of the Korean Bone and Joint Tumor Society
;
: 66-71, 2012.
Artigo
em Coreano
| WPRIM
| ID: wpr-30028
ABSTRACT
PURPOSE:
We analyzed treatment result to examine the outcome for patients with sacral chordoma and to determine relevant prognostic factors. MATERIALS ANDMETHODS:
We retrospectively reviewed 19 patients with sacral chordoma seen at out institution between 1990 and 2010. There were 9 men and 10 women with mean age of 56 years. The average follow up was 63 months (range, 25-144 months). 15 patient received surgical treatment, six of these patient had wide, eight had marginal, one had intralesional margin and 4 patient treated with Radiation therapy only.RESULTS:
The disease free and overall survival rate for all 19 patients was 34.7% and 79.7% at 5-years, respectively. Statistical analysis using the log-rank test revealed no significant difference between the surgery and radiation therapy groups in overall survival (p=0.54). Nine of 19 patients had local recurrence at a median of 2.5 years postoperatively. Seven of these 9 patients had distant metastasis at a median of 4.5 years postoperatively. Among the variables, tumor size (p=0.033) and tumor involvement of above S3 (p=0.032) were independent prognostic factor for overall survival. Nine of 15 patients who received surgical treatment had postoperative complication such as voiding difficulty and incontinence.CONCLUSION:
Careful consideration of the patient general condition and predictable complication of the treatment might be the best way to improve patient's survival and quality of life.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complicações Pós-Operatórias
/
Qualidade de Vida
/
Recidiva
/
Sacro
/
Cordoma
/
Taxa de Sobrevida
/
Estudos Retrospectivos
/
Seguimentos
/
Metástase Neoplásica
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Journal of the Korean Bone and Joint Tumor Society
Ano de publicação:
2012
Tipo de documento:
Artigo
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