Expression of Runx2/Cbfa1 in the developing pulpo-dentinal complex of postnatal mice / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 373-376, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-300294
ABSTRACT
<p><b>OBJECTIVE</b>To study the expression of Runx2/Cbfa1 in the developing dentin and differentiating odontoblasts.</p><p><b>METHODS</b>A postnatal mice teeth developing model was built histologically. Immunohistochemical technique was adopted to determine the expression of Runx2/Cbfa1 in the developing pulpo-dentinal complex in mice.</p><p><b>RESULTS</b>Runx2/Cbfa1 was merely present in predentin in the exact and before the 11th day's postnatal stages. Meanwhile, it was positively located in odontoblasts and dental pulp cells in root region, but negatively in coral part after the 11th day's stages.</p><p><b>CONCLUSION</b>Runx2/Cbfa1 may play an important role in the deposing of tooth dentin and in the differentiating of odontoblasts and pulp cells.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dente
/
Diferenciação Celular
/
Polpa Dentária
/
Dentina
/
Subunidade alfa 1 de Fator de Ligação ao Core
/
Odontoblastos
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Chinês
Revista:
West China Journal of Stomatology
Ano de publicação:
2005
Tipo de documento:
Artigo
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