Advances in application of Jurkat cell model in research on infectious diseases / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 236-242, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-300357
ABSTRACT
Infectious diseases can be caused by multiple pathogens, which can produce specific immune response in human body. The immune response produced by T cells is cellular immunity, which plays an important role in the anti-infection process of human body, and can participate in immunological protection and cause immunopathology. The outcome of various infectious diseases is closely related to cellular immune function, especially the function of T cells. Jurkat cells belong to the human acute T lymphocyte leukemia cell line. Jurkat cell model can simulate the function T lymphocytes, so it is widely used in the in vitro studies of T cell signal transduction, cytokines, and receptor expression, and can provide reference and guidance for the treatment of various infectious diseases and the research on their pathogenesis. The Jurkat cell model has been widely used in the in vitro studies of viral diseases and atypical pathogens, but parasitic infection studies using the Jurkat cell model are still rare. This article reviews advances in the application of Jurkat cell model in the research on infectious diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Linfócitos T
/
Infecções por Deltaretrovirus
/
Infecções por HIV
/
Doenças Transmissíveis
/
Células Jurkat
/
Infecções por Vírus Epstein-Barr
/
Enterovirus Humano A
/
Infecções por Enterovirus
/
Alergia e Imunologia
Tipo de estudo:
Guia de Prática Clínica
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2018
Tipo de documento:
Artigo
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