Research progress on the animal models and treatment strategies of diabetic foot ulcer / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 97-105, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-300817
ABSTRACT
The suitable experimental animal model is important in research of pathogenesis and therapeutic strategies of diabetic foot ulcer, and the murine model is the most commonly used one at present. It can be divided into two types the animal model simulating pathological conditions and the model simulating clinical symptoms. This article reviews the current research progress on the mechanisms of diabetic ulcer pathogenesis, and relevant treatment strategies, including the inhibition of matrix metalloproteinases (MMPs) expression, promotion of angiogenesis and anti-inflammatory therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Terapêutica
/
Pé Diabético
/
Neovascularização Fisiológica
/
Metaloproteinases da Matriz
/
Usos Terapêuticos
/
Modelos Animais de Doenças
/
Inibidores de Metaloproteinases de Matriz
/
Genética
/
Metabolismo
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2017
Tipo de documento:
Artigo
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