Human protamines and the developing spermatid: their structure, function, expression and relationship with male infertility / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 315-324, 2003.
Artigo
em Inglês
| WPRIM
| ID: wpr-300879
ABSTRACT
During spermiogenesis, the protamine proteins play an integral role in spermatid chromatin compaction. Recent research has focused on many facets of protamine biology, including protamine gene and protein structure/function relationships, mechanisms of protamine expression regulation and involvement of the protamines in male fertility. In this paper, we review our current understanding of the structure and function of the protamine-1 (P1) and protamine-2 (P2) proteins and genes, the expression and regulation of these genes and the relationship between the protamines and male fertility. In addition, we offer a brief outlook on future investigation into protamine proteins.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Espermátides
/
Dados de Sequência Molecular
/
Protaminas
/
Química
/
Regulação da Expressão Gênica
/
Sequência de Aminoácidos
/
Genética
/
Infertilidade Masculina
/
Metabolismo
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Asian Journal of Andrology
Ano de publicação:
2003
Tipo de documento:
Artigo
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