Epigenetics and neural stem cell commitment / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 241-248, 2007.
Artigo
em Inglês
| WPRIM
| ID: wpr-300957
ABSTRACT
Neural stem cell is presently the research hotspot in neuroscience. Recent progress indicates that epigenetic modulation is closely related to the self-renewal and differentiation of neural stem cell. Epigenetics refer to the study of mitotical/meiotical heritage changes in gene function that cannot be explained by changes in the DNA sequence. Major epigenetic mechanisms include DNA methylation, histone modification, chromatin remodeling, genomic imprinting, and non-coding RNA. In this review, we focus on the new insights into the epigenetic mechanism for neural stem cells fate.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Células-Tronco
/
Diferenciação Celular
/
Impressão Genômica
/
Metilação de DNA
/
Montagem e Desmontagem da Cromatina
/
Epigênese Genética
/
Neurônios
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Neuroscience Bulletin
Ano de publicação:
2007
Tipo de documento:
Artigo
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