Alcohol Drinking, Cigarette Smoking and Risk of Colorectal Cancer in the Korean Multi-center Cancer Cohort
Journal of Cancer Prevention
;
: 147-152, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-30133
ABSTRACT
BACKGROUND:
The present study aimed to examine the association between cigarette smoking, alcohol consumption and colorectal cancer risk among Korean adults.METHODS:
Data from the Korean Multi-center Cancer Cohort between 1993 and 2005 were analyzed. The study population comprised 18,707 subjects aged older than 20 years old. The subjects were followed until December 31, 2011 (median follow-up of 11.2 years). The Cox proportional hazard model was used to estimate the hazard ratio (HR) and 95% confidence intervals of cigarette smoking and alcohol consumption for colorectal cancer risk.RESULTS:
In men, longer duration and higher average amount of alcohol consumption were associated with elevated risk of colorectal cancer (HR 1.93 [1.17-3.18] for > or = 30 years of consumption compared to non-drinkers; HR 2.24 [1.31-3.84] for > or = 30 g/d). Former smokers showed a non-significantly elevated risk of colorectal cancer in men. There was no apparent association between alcohol consumption or cigarette smoking and colorectal cancer risk among women.CONCLUSIONS:
Alcohol consumption was associated with increased colorectal cancer risk among Korean men, and both a longer duration and a higher amount of consumption were associated with elevated risk.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Consumo de Bebidas Alcoólicas
/
Neoplasias Colorretais
/
Fumar
/
Modelos de Riscos Proporcionais
/
Estudos Prospectivos
/
Estudos de Coortes
/
Seguimentos
/
Produtos do Tabaco
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Journal of Cancer Prevention
Ano de publicação:
2015
Tipo de documento:
Artigo
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