Correlation between neuroretinal rim area/retinal nerve fiber layer thickness and differential light sensitivity in visual field in primary open angle glaucoma / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To explore the relationship between neuroretinal rim area (RA) /retinal nerve fiber layer (RNFL) thickness and differential light sensitivity (DLS) in visual field in primary open angle glaucoma (POAG).</p><p><b>METHODS</b>Fifty-one eyes of 51 patients with POAG were examined with HRT II, GDx VCC, and Octopus 101 for RA, RNFL thickness, and DLS. Their correlations were evaluated with linear and logarithmic regression models globally and for individual sectors.</p><p><b>RESULTS</b>In all the considered patients, visual field DLS was significantly correlated with neuroretinal RA or RNFL thickness globally and in individual sectors. Logarithmic fits were significantly better than linear fits for the global data and in most sectors. In preperimetric glaucoma, such correlations were weak and linear (R2 = 0.01-0.26). However, in perimetric glaucoma, the correlations were much stronger and curvilinear model gave the better fit (R2 = 0.15-0.84). Neuroretinal RA and RNFL thickness were linearly correlated.</p><p><b>CONCLUSION</b>Neuroretinal RA, RNFL thickness, and DLS in visual field were well correlated in POAG.</p>