New insight into DNA methylation in CML and its effect on clinical outcome--review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1482-1486, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-302211
ABSTRACT
All kinds of tumors have their specific DNA methylation patterns. The study of DNA methylation changes in chronic myelogenous leukemia includes (1) the hypomethylation of carcinogenic gene, (2) the hypermethylation of tumor-suppressing gene, and (3) the hypermethylation of fusion gene. In this paper, DNA methylation change in chronic myeloid leukemia (CML) and its role in clinical stages and evaluation of prognosis were reviewed so as to illuminate the relationship between DNA methylation and CML.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Prognóstico
/
Leucemia Mielogênica Crônica BCR-ABL Positiva
/
Metilação de DNA
/
Diagnóstico
/
Genética
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2008
Tipo de documento:
Artigo
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