A new steroidal alkaloid from the bulbus of Fritillaria wabuensia / 药学学报

ABSTRACT

<p><b>AIM</b>To investigate the chemical constituents of the bulbs of Fritillaria wabuensia.</p><p><b>METHODS</b>Chromatography techniques were used to isolate the chemical constituents. EI-MS, 1HNMR, 13 CNMR and DEPT were used to determine the structures of the isolated constituents.</p><p><b>RESULTS</b>Three alkaloids were isolated from the bulbs of Fritillaria wabuensia, and were identified as imperialine (I), imperialine-beta-N-oxside (II), isoverticine-beta-N-oxide (III).</p><p><b>CONCLUSION</b>Isoverticine-beta-N-oxide was isolated from the bulbs of Fritillaria wabuensia for the first time. Isoverticine-beta-N-oxide is a new alkaloid.</p>