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Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines
Asian Pacific Journal of Tropical Biomedicine ; (12): 826-829, 2012.
Artigo em Inglês | WPRIM | ID: wpr-303595
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the cytotoxic effect of Elaeis guineensis methanol extract on MCF-7 and Vero cell.</p><p><b>METHODS</b>In vitro cytotoxicity was evaluated in by MTT assay. Cell morphological changes were observed by using light microscope.</p><p><b>RESULTS</b>The MTT assay indicated that methanol extract of the plant exhibited significant cytotoxic effects on MCF-7. Morphological alteration of the cell lines after exposure with Elaeis guineensis extract were observed under phase contrast microscope in the dose dependent manner.</p><p><b>CONCLUSIONS</b>The results suggest the probable use of the Elaeis guineensis methanol extract in preparing recipes for cancer-related ailments. Further studies on isolation of metabolites and their in vivo cytotoxicity are under investigation.</p>
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Células Vero / Extratos Vegetais / Chlorocebus aethiops / Química / Folhas de Planta / Arecaceae / Proliferação de Células / Metanol / Relação Dose-Resposta a Droga Limite: Animais / Humanos Idioma: Inglês Revista: Asian Pacific Journal of Tropical Biomedicine Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Células Vero / Extratos Vegetais / Chlorocebus aethiops / Química / Folhas de Planta / Arecaceae / Proliferação de Células / Metanol / Relação Dose-Resposta a Droga Limite: Animais / Humanos Idioma: Inglês Revista: Asian Pacific Journal of Tropical Biomedicine Ano de publicação: 2012 Tipo de documento: Artigo