Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines
Asian Pacific Journal of Tropical Biomedicine
;
(12): 826-829, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-303595
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the cytotoxic effect of Elaeis guineensis methanol extract on MCF-7 and Vero cell.</p><p><b>METHODS</b>In vitro cytotoxicity was evaluated in by MTT assay. Cell morphological changes were observed by using light microscope.</p><p><b>RESULTS</b>The MTT assay indicated that methanol extract of the plant exhibited significant cytotoxic effects on MCF-7. Morphological alteration of the cell lines after exposure with Elaeis guineensis extract were observed under phase contrast microscope in the dose dependent manner.</p><p><b>CONCLUSIONS</b>The results suggest the probable use of the Elaeis guineensis methanol extract in preparing recipes for cancer-related ailments. Further studies on isolation of metabolites and their in vivo cytotoxicity are under investigation.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Células Vero
/
Extratos Vegetais
/
Chlorocebus aethiops
/
Química
/
Folhas de Planta
/
Arecaceae
/
Proliferação de Células
/
Metanol
/
Relação Dose-Resposta a Droga
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Asian Pacific Journal of Tropical Biomedicine
Ano de publicação:
2012
Tipo de documento:
Artigo
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