Association between perioperative bleeding post percutaneous coronary intervention and 1 year clinical outcomes in elderly patients / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 26-30, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-303773
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the association between perioperative bleeding post percutaneous coronary intervention (PCI) and 1 year adverse cardiovascular events in elderly patients.</p><p><b>METHODS</b>From June 2006 to August 2011, 1 105 elderly ( ≥ 75 years) patients undergoing PCI in Fuwai Hospital were prospectively included. Patients were divided into peri-procedure bleeding group (n = 153) and no bleeding group (n = 952). Cox proportional hazards model was performed to evaluate the independent effect of bleeding on the composite endpoint of death and myocardial infarction.</p><p><b>RESULTS</b>BARC 2 grade bleeding occurred in 9.5% (105/1 105) patients. The rate of BARC ≥ 2 grade bleeding was 11.8% (130/1 105) , and the access site-related bleeding accounted for 62.7% (96/153) of all bleeding. The composite endpoint of 1 year death and myocardial infarction was higher in bleeding group (9.2% (14/153) vs. 4.2% (40/952), P = 0.008) . The 1 year cardiac death was higher in bleeding group (3.9% (6/153) vs. 0.8% (8/952), P = 0.007), but the rate of non-cardiac death was similar between bleeding group and no bleeding group (P = 0.360). Cox proportional hazards model analysis showed that HR of 1 year death and myocardial infarction in BARC ≥ 2 grade bleeding patients was 2.368 (95%CI1.201-4.669, P = 0.013) compared with no bleeding patients.</p><p><b>CONCLUSION</b>Perioperative bleeding post PCI is an independent predictor of 1 year adverse outcomes in elderly patients( ≥ 75 years).</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Modelos de Riscos Proporcionais
/
Fatores de Risco
/
Resultado do Tratamento
/
Intervenção Coronária Percutânea
/
Hemorragia
/
Infarto do Miocárdio
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Idoso
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Cardiology
Ano de publicação:
2015
Tipo de documento:
Artigo
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