Acute encephalitis following rubella virus infection

ABSTRACT

Two patients(17-year-old and 23-year-old men) with rubella infection had maculopapular rash, lymphadenopathy and lower grade fever. Several days after the onset of rash, they showed convulsions and fell in confused states. The CSF examinaion showed lymphocytic pleocytosis, increased protein and normal glucose level. Rubella infection and its CNS complications in both cases were diagnosed by detection of IgG and IgM in serum and CSF employing radioimmunoassay. Imaging study was done. A brain magnetic resonance imaging(MRI) findings were normal but brain single photon emmission computed bomography(SPECT) sjhowed slightly decreased uptake of left frontal and temporal lobe in one case. Both patients were recovered without any sequelae.