Phloroglucinol combined with parecoxib for cystospasm after transurethral resection of the prostate / 中华男科学杂志
National Journal of Andrology
;
(12): 641-644, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-304697
ABSTRACT
<p><b>Objective</b>To evaluate the effect and safety of phloroglucinol combined with parecoxib on cystospasm after transurethral resection of the prostate (TURP).</p><p><b>METHODS</b>We conducted a prospective randomized case-control study on 98 patients treated by TURP. After operation, the patients were randomly assigned to a treatment (n=50) and a control group (n=48), the former treated by intravenous injection of 80 mg phloroglucinol qd plus 40 mg parecoxib bid while the latter given 80 mg phloroglucinol only, both for 3 successive days. Then we recorded the frequency and duration of cystospasm, visual analogue scales (VAS), adverse reactions, post-operative bladder irrigation time, catheter-indwelling time, and hospital stay and compared them between the two groups of patients.</p><p><b>RESULTS</b>Compared with the controls, the patients in the treatment group showed a significantly lower frequency of cystospasm ([1.95±0.14] vs [0.70±0.65] times, P<0.01), duration of cystospasm ([0.44±0.21] vs [0.12±0.14] min, P<0.01), and VAS score (2.70±1.80 vs 1.90±1.30, P<0.01) at 48-72 hours after TURP, but no statistically significant differences were found between the control and treatment groups in the post-operative bladder irrigation time ([2.75±0.87] vs [2.64±0.83] d, P>0.05), catheter-indwelling time ([3.52±0.32] vs [3.44±0.42] d, P>0.05), and hospital stay ([5.23±0.81] vs [5.10±0.73] d, P>0.05), and no obvious adverse reactions were observed in either of the two groups.</p><p><b>CONCLUSIONS</b>Phloroglucinol combined with parecoxib is more effective and safer than phloroglucinol alone in relieving postoperative cystospasm after TURP.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Floroglucinol
/
Período Pós-Operatório
/
Hiperplasia Prostática
/
Espasmo
/
Bexiga Urinária
/
Estudos de Casos e Controles
/
Estudos Prospectivos
/
Resultado do Tratamento
/
Ressecção Transuretral da Próstata
/
Usos Terapêuticos
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
/
Fatores de risco
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2016
Tipo de documento:
Artigo
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