Changes and analysis of peripheral white blood cells and lymphocyte subsets for patients with influenza B virus infection / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 32-34, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-304989
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the characters and changes of peripheral white blood cells and lymphocyte subsets of patients with influenza B virus infection and to provide evidences for diagnosis, treatment and prognosis of influenza B virus infection.</p><p><b>METHODS</b>Peripheral white blood cell parameters and the percentages of lymphocyte subsets in acute and recovery phases of 47 cases of influenza B virus infection patients(32 mild cases and 15 severe cases)were investigated and analyzed,and compared respectively with those of 38 cases of healthy people using whole blood cell analysis and flow cytometry.</p><p><b>RESULTS</b>Peripheral white blood cell counts of mild cases decreased greatly but peripheral white blood cell counts and the neutrophils of severe cases increased significantly in acute phase; the peripheral lymphocytes, CD3, CD4, CD8 and CD19 of all patients with influenza B virus infection decreased greatly in acute phase and quickly recovered in recovery phase;there were similar characteristics of change in NK cells between patients with influenza B virus and healthy people. NK cells absolute counts of severe cases decreased significantly in acute phase.</p><p><b>CONCLUSION</b>Peripheral white blood cell counts and the neutrophils of increased significantly in acute phase and the great decrease of NK cells absolute counts of patients with influenza B virus infection may suggest the severe tendency of diseases.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vírus da Influenza B
/
Virologia
/
Sangue
/
Células Matadoras Naturais
/
Antígenos CD
/
Subpopulações de Linfócitos
/
Alergia e Imunologia
/
Influenza Humana
/
Contagem de Leucócitos
/
Leucócitos
Tipo de estudo:
Estudo prognóstico
Limite:
Adolescente
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2013
Tipo de documento:
Artigo
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