FibroScan can be used to diagnose the size of oesophageal varices in patients with HBV-related cirrhosis / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 470-473, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-305006
ABSTRACT
<p><b>OBJECTIVE</b>To study ability of FibroScan (FS) in diagnosing the size of oesophageal varices (OV) in patients with HBV-related cirrhosis.</p><p><b>METHODS</b>A total of 158 patients with HBV-related liver cirrhosis were enrolled in the study. The relation between the presence of OV assessed by endoscopy, and liver stiffness measurement by Fibroscan was studied, and ROC curves were drawn to assess the diagnostic ability of FS value.</p><p><b>RESULTS</b>For the patients without OV, mild OV, moderate OV, and severe OV, their corresponding FS values were (21.7 +/- 9.9) kPa, (32.1 +/- 13.6) kPa, (42.3 +/- 20.0) kPa and (54.5 +/- 16.2) kPa, respectively. Significant difference was found among the groups (P < 0.001) and also between any two groups (P < 0.05). ROC curve for the diagnosis of with vs. without OV, <moderate vs. > moderate OV, and < severe vs. severe OV were 0.798 (95% CI 73.1%-86.5%), 0.823 (95% CI 74.5%-90.0%) and 0.879 (95% CI 80.8%-95.0%), respectively, with corresponding FS cut-off value of 23.3 kPa, 31.5 kPa and 34.6 kPa.</p><p><b>CONCLUSION</b>Liver stiffness measurement allows to predict the sizes of oesophageal varices in patients with HBV-related cirrhosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Diagnóstico por Imagem
/
Varizes Esofágicas e Gástricas
/
Diagnóstico
/
Técnicas de Imagem por Elasticidade
/
Fígado
/
Cirrose Hepática
/
Métodos
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2012
Tipo de documento:
Artigo
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