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Multiple viral transmission chains of enterovirus 71 co-circulated in Jilin Province during 2009-2010 / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology ; (6): 273-275, 2012.
Artigo em Chinês | WPRIM | ID: wpr-305061
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the genetic characterization of enterovirus type71 (EV71) associated with hand foot and mouth disease (HFMD) epidemics in Jilin province, during 2009-2010.</p><p><b>METHODS</b>Randomly selected 31 representative EV71 strains from the cases of 8 prefectures to amplify and sequences of VP1 genes of EV71 strains, and analyzed with Bioedit and Mega4.0 program.</p><p><b>RESULTS</b>All representative 31 EV71 strains belong to C4a subgenotype, the homology of nucleotide in VP1 region among the 31 EV71 strains were 94. 5%-100. 0%, and were clustered into 5 transmission chains respectively. 25 strains out of 31 strains were associated with a predominant transmission chain, and circulating in 8 prefectures, while other 6 strains clustered into 4 lineages.</p><p><b>CONCLUSION</b>Multiple transmission chains of EV71 C4a subgenotype were co-circulating in Jilin province during 2009-2010, and a predominant transmission chain was circulating in 8 prefectures, associated with HFMD outbreaks of Jilin province.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Filogenia / Virologia / Dados de Sequência Molecular / China / Epidemiologia / Surtos de Doenças / Classificação / Enterovirus Humano D / Fezes / Genética Limite: Humanos País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Experimental and Clinical Virology Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Filogenia / Virologia / Dados de Sequência Molecular / China / Epidemiologia / Surtos de Doenças / Classificação / Enterovirus Humano D / Fezes / Genética Limite: Humanos País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Experimental and Clinical Virology Ano de publicação: 2012 Tipo de documento: Artigo