HIV-1 molecular epidemiological survey of drug users in Jiangxi province / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 14-16, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-305510
ABSTRACT
<p><b>OBJECTIVE</b>To investigate HIV-1 molecular epidemiology of drug users in Jiangxi Province to analyze epidemic situation, subtype, origin of strain, and variation, and to provide information for prevention and control of AIDS.</p><p><b>METHODS</b>Combining principles of traditional epidemiology and molecular epidemiology, the authors analyzed the epidemiologically related factors, the gene sequences and systematic mutation of HIV-1 gene in nine drug users in Jiangxi province.</p><p><b>RESULTS</b>The HIV spread through the drug users in Jiangxi not only by injection but also by sexual contacts. The main epidemic strain found by sequence analysis was HIV-1 CRF01-AE that was closely related to the strain among drug users in Vietnam and Guangxi Zhuang Autonomous Region, with the average gene distance of 9.00 +/- 2.27 from the Vietnam strain. The origin of strain among drug users in the province was entirely the same.</p><p><b>CONCLUSION</b>At present, HIV-1 CRF01-AE strain has spread in the whole province among the drug users. Vigorous behavioral interventions should be developed in drug users and un-safe sexual behavior population to prevent the epidemic.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Variação Genética
/
Virologia
/
DNA Viral
/
Abuso de Substâncias por Via Intravenosa
/
Química
/
China
/
Epidemiologia
/
Surtos de Doenças
/
Síndrome da Imunodeficiência Adquirida
/
HIV-1
Limite:
Adulto
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2007
Tipo de documento:
Artigo
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