Diagnosis of the deep partial-thickness burn wound of Skh-1 mouse with Optical Coherence Tomography / 中华烧伤杂志
Chinese Journal of Burns
;
(6): 272-275, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-305593
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the application value of Optical Coherence Tomography (OCT) in the diagnosis of the depth of burn wound.</p><p><b>METHODS</b>Deep partial-thickness scald models of Skh-1 mice were reproduced using self-made steam scald appliance. The scald wounds were scanned with OCT 3 hours, or 3 and 8 days after injury respectively. Scanned wound tissue was harvested for histological examination right after each episode of OCT imaging. Normal skin of mice was scanned and examined with the above-mentioned methods at the same time.</p><p><b>RESULTS</b>Compared with those of the normal skin, collagen in the dermis was denatured after steam scald, and it was imaged as vanishing or reduction in birefringence in OCT detection. The structure change intensity was related to the pathological process of the wounds and consistent with the corresponding histological results.</p><p><b>CONCLUSIONS</b>OCT is a noninvasive technique. It can be used to diagnose the depth of burn wound in real time.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cicatrização
/
Queimaduras
/
Diagnóstico por Imagem
/
Cintilografia
/
Tomografia de Coerência Óptica
/
Modelos Animais de Doenças
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Burns
Ano de publicação:
2010
Tipo de documento:
Artigo
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