Oral paroxetine for premature ejaculation: a randomized controlled study / 中华男科学杂志
National Journal of Andrology
; (12): 923-925, 2011.
Article
em Zh
| WPRIM
| ID: wpr-305762
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To validate the therapeutic efficacy of paroxetine in the treatment of premature ejaculation (PE).</p><p><b>METHODS</b>Eighty PE patients up to the inclusion criteria were equally randomized to an experimental and a control group. We observed all the patients for 4 weeks and recorded the baseline data on intravaginal ejaculatory latency time (IELT) and sexual satisfaction scores, followed by oral medication of paroxetine at 20 mg/d for the patients in the experimental group and placebo for the controls. Thirty days after the treatment, we again recorded IELT and sexual satisfaction scores of the patients.</p><p><b>RESULTS</b>After the treatment, the experimental group showed significantly prolonged IELT ([5.75 +/- 1.24] min) and increased sexual satisfaction score (6.4 +/- 1.2) as compared with the baseline data ([0.89 +/- 0.21] min and [2.7 +/- 0.9]) (P < 0.01). The control group exhibited no significant differences before and after the medication either in the mean IELT or in sexual satisfaction scores ([1.06 +/- 0.28] min vs [0.97 +/- 0.18] min and 3.6 +/- 1.3 vs 3.1 +/- 1.1, P > 0.05).</p><p><b>CONCLUSION</b>Oral medication of paroxetine at 20 mg/d for 30 days could improve IELT and sexual satisfaction in PE patients.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Disfunções Sexuais Fisiológicas
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Resultado do Tratamento
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Inibidores Seletivos de Recaptação de Serotonina
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Paroxetina
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Usos Terapêuticos
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Tratamento Farmacológico
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Ejaculação
Tipo de estudo:
Clinical_trials
Limite:
Adult
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Humans
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Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2011
Tipo de documento:
Article