The effect of neoadjuvant chemotherapy on estrogen and progesterone receptor expression in breast carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 1011-1013, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-306146
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of neoadjuvant chemotherapy on estrogen receptor (ER) and progesterone receptor (PR) expression in breast carcinoma.</p><p><b>METHODS</b>Samples were obtained from 31 patients with breast carcinoma who received neo-adjuvant chemotherapy, ER or PR expressions were analyzed in preoperative core biopsies and final surgical specimens.</p><p><b>RESULTS</b>ER level was up-regulated in 13 (41.9%) out of 31 cases, PR level was up-regulated in 10 (32.3%). Both ER level and PR level were up-regulated in 8 (25.8%) out of 31 cases.</p><p><b>CONCLUSIONS</b>Neoadjuvant chemotherapy may impact the hormone receptor status, ER and PR expression re-analysis in final surgical specimens is recommended.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias da Mama
/
Imuno-Histoquímica
/
Epirubicina
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Receptores de Progesterona
/
Receptores de Estrogênio
/
Seguimentos
/
Quimioterapia Adjuvante
/
Paclitaxel
/
Terapia Neoadjuvante
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Surgery
Ano de publicação:
2005
Tipo de documento:
Artigo
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