Expression of Nusap1 in the surgical margins of hepatocellular carcinoma and its association with early recurrence / 南方医科大学学报
Journal of Southern Medical University
;
(12): 937-inside back cover, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-306434
ABSTRACT
<p><b>OBJECTIVE</b>To detect the expression of Nusap1 of surgical margins in hepatocellular carcinoma (HCC) and investigate its association with early tumor recurrence.</p><p><b>METHODS</b>The expression of Nusap1 in the surgical margins of HCC, which were histopathologically negative for tumor cells, was examined using immunohistochemistry in 61 HCC cases.</p><p><b>RESULTS</b>Fifteen of 21 (71.4%) cases with immunohistochemical positivity for Nusap1 expression in the surgical margins had early recurrence of HCC, a rate significantly higher than that in patients with negative Nusap1 expression (12/40, 30%) (P<0.05).</p><p><b>CONCLUSIONS</b>Nusap1 expression in the surgical margins of HCC is closely correlated to early postoperative recurrence and can serve as an indicator for predicting early recurrence of HCC.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Cirurgia Geral
/
Imuno-Histoquímica
/
Carcinoma Hepatocelular
/
Neoplasias Hepáticas
/
Metabolismo
/
Proteínas Associadas aos Microtúbulos
/
Recidiva Local de Neoplasia
Limite:
Adolescente
/
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2013
Tipo de documento:
Artigo
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