Diagnosis of obstructive coronary artery disease using CT coronary angiography combined with CT first-pass myocardial perfusion imaging at rest / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To assess the feasibility and accuracy of CT coronary angiography (CTCA) combined with CT first-pass myocardial perfusion imaging (CT first-pass MPI) at rest for diagnosis of obstructive coronary artery disease (CAD).</p><p><b>METHODS</b>Fifty-five patients, suspected or diagnosed as CAD, were performed with CTCA and CAG within 2 weeks. CT first-pass MPI detected myocardial ischemia through analyzing the raw date of CTCA.</p><p><b>RESULTS</b>Comparison with the results of CAG, the sensibility, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CT first-pass MPI at rest for detecting obstructive CAD were 84.6%, 68.8%, 86.8%, 64.7% and 80.0%, respectively; and 92.3%, 93.8%, 97.3%, 83.3%, 92.7% for CTCA combined with CT first-pass MPI, respectively.</p><p><b>CONCLUSION</b>CTCA combined with CT first-pass MPI at rest could detect obstructive CAD feasible and accurately.</p>