Vasculogenic mimicry in tongue squamous cell carcinoma / 南方医科大学学报
Journal of Southern Medical University
;
(12): 593-597, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-306505
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the presence of vasculogenic mimicry (VM) in tongue squamous cell carcinoma and explore its clinical significance.</p><p><b>METHODS</b>Forty-two surgical specimens of tongue squamous cell carcinoma were examined for the presence of VM using HE staining and double staining of CD34 and PAS.</p><p><b>RESULTS</b>Of the 42 specimens, 18 (42.86%) showed the presence of VM. VM was not correlated with the patients' age or gender, but with lymph node metastasis and the grade of tumor differentiation. Compared with tumors without VM, the tumors with VM had a significantly higher rate of lymph node metastasis (P<0.05) and a lower grade of differentiation (P<0.05).</p><p><b>CONCLUSION</b>VM can be present in tongue squamous cell carcinoma, and the poorly differentiated tumors contain more VM, which is associated with a greater likeliness of lymph node metastasis and a poorer prognosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias da Língua
/
Carcinoma de Células Escamosas
/
Neovascularização Patológica
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2013
Tipo de documento:
Artigo
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