The clinical application of hydrogen magnetic resonance spectroscopy combining with diffusion weight imaging in brain gliomas grading / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 470-474, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-306536
ABSTRACT
The present study was aimed to investigate the function of diffusion weight imaging (DWI) combining with magnetic resonance spectroscopy (MRS) in the grading of brain gliomas. 12 cases low grade and 17 cases high grade of brain gliomas patients were examined with DWI and MRS, with all tumors confirmed by pathology in advance. The apparent diffusion coefficient (ADC) values, their corresponding metabolite ratios of Cho/Cr, Cho/NAA and tumor cellularities of tumor solid enhanced parts were measured. The ratios of Cho/Cr and Cho/NAA and their corresponding ADC values had significant differences between their high and low grade gliomas values, respectively. The ADC values demonstrated a negative correlation with Cho/Cr, Cho/NAA, and a significant negative correlated with Cho/Cr. And the ADC values demonstrated strong negative correlations with tumor cellularities. DWI combining with MRS could provide more valuable information in evaluating gliomas grading.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Neoplasias Encefálicas
/
Espectroscopia de Ressonância Magnética
/
Imagem de Difusão por Ressonância Magnética
/
Diagnóstico
/
Gradação de Tumores
/
Glioma
/
Hidrogênio
/
Métodos
Tipo de estudo:
Estudo diagnóstico
Limite:
Adolescente
/
Adulto
/
Idoso
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2011
Tipo de documento:
Artigo
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