Cigarette smoking increases risk for incident metabolic syndrome in Chinese men-Shanghai diabetes study / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 475-482, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-306836
ABSTRACT
<p><b>OBJECTIVE</b>To determine whether smoking increases the risk for developing metabolic syndrome (MetS) in Chinese men.</p><p><b>METHODS</b>A total of 693 men with no MetS at baseline were followed for 2.9-5.5 years. Subjects were divided into nonsmokers, ex-smokers, and current smokers according to baseline smoking status.</p><p><b>RESULTS</b>After adjusting for age, education level, alcohol intake, fasting plasma insulin, HOMA-IR index, and BMI at baseline and weight change, current smokers were dose-dependently associated with increased risk for developing new MetS compared with nonsmokers. The odds ratio (OR) was 2.131 (95% CI, 1.264, 3.592; P<0.01) for the NCEPIII definition or 3.083 (95% CI, 1.807, 5.295; P<0.01) for the JCDCG definition of MetS. Ex-smokers who had quit for ≥13 years significantly decreased the risk for developing new MetS defined by the JCDCG definition. Compared with nonsmokers, current smokers were significantly associated with increased incidence of hypertriglyceridemia and low HDL-C.</p><p><b>CONCLUSION</b>Smoking is a risk factor for developing MetS in Chinese men after adjusting for age, education level, alcohol intake, fasting plasma insulin, HOMA-IR, BMI, and weight change. This could be due to an increased incidence of dyslipidemia. Smoking cessation for >13 years decreased the risk for developing MetS defined by the JCDCG definition.</p>
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DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sangue
/
Glicemia
/
Hipertrigliceridemia
/
Fumar
/
Índice de Massa Corporal
/
Razão de Chances
/
China
/
Epidemiologia
/
Fatores de Risco
/
Seguimentos
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Aged80
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Biomedical and Environmental Sciences
Ano de publicação:
2011
Tipo de documento:
Artigo
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