Influence of the number of removed axillary lymph nodes on the prognosis of node-negative primary breast cancer / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 457-460, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-307364
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the relationship between the number of removed axillary lymph nodes and prognosis of axillary node-negative breast cancer.</p><p><b>METHODS</b>The clinicopathological data of 655 patients with breast cancer were analyzed retrospectively. The disease-free survival curves were generated according to the number of removed axillary lymph nodes using Kaplan-Meier plots. The correlation between the co-variables and rate of breast cancer-related events was analyzed using Cox model.</p><p><b>RESULTS</b>The overall five year-disease free survival rate of the 655 cases was 94.4%. The rate of patients with lymph node number ≤ 12 was 90.3%, and that of lymph node number > 12 was 96.5%, with a statistically significant difference (P = 0.009). Significantly less breast cancer-related events were observed in patients with lymph node number > 12 (15/426, 3.5%) than that in patients with lymph node number ≤ 12 (22/229, 9.6%) (P = 0.009).</p><p><b>CONCLUSIONS</b>When axillary node dissection is indicated, dissection of lymph nodes >12 leads to much less breast cancer-related events than that in patients with dissected lymph node ≤ 12. The more lymph nodes are dissected, the more accurate prognosis can be estimated.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Axila
/
Cirurgia Geral
/
Neoplasias da Mama
/
Modelos de Riscos Proporcionais
/
Taxa de Sobrevida
/
Estudos Retrospectivos
/
Seguimentos
/
Carcinoma Ductal de Mama
/
Carcinoma Intraductal não Infiltrante
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Oncology
Ano de publicação:
2012
Tipo de documento:
Artigo
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