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Analysis of the relative etiology of non-obstructive azoospermia / 中华男科学杂志
National Journal of Andrology ; (12): 616-622, 2004.
Artigo em Chinês | WPRIM | ID: wpr-308285
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the levels and changes of sexual hormone in serum and seminal plasma, and the epidermal growth factor (EGF), alpha-glucosidase, and fructose in the seminal plasma of non-obstructive azoospermic patients, and to assess the significance of the analysis of their chromosomes.</p><p><b>METHODS</b>Thirty-six non-obstructive azoospermic males and 26 normal males were chosen. The results in reproductive endocrine and genetics obtained by radioimmunoassay, colorimetry, and chromosomes G and C banding assay were compared and analyzed to explore into the causes of infertility.</p><p><b>RESULTS</b>The levels of FSH, LH, PRL and E2 in the serum of the non-obstructive azoospermic patients were higher than those of the control group, but the T level had no significant difference between the two groups. There were no obvious differences in the sexual hormones except in FSH of the seminal plasma. There were 2 cases of abnormal sex chromosomes, 2 cases of big Y chromosomes and 7 cases of small Y chromosomes in the non-obstructive azoospermic patients. No correlation was found between EGF and fructose in the seminal plasma.</p><p><b>CONCLUSION</b>The level of sexual hormone in serum, alpha-glucosidase in seminal plasma and abnormal chromosomes might be closely related to non-obstructive azoospermia.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sêmen / Hormônios Esteroides Gonadais / Estudos de Casos e Controles / Química / Bandeamento Cromossômico / Cromossomos Humanos Y / Fator de Crescimento Epidérmico / Alfa-Glucosidases / Azoospermia / Genética Tipo de estudo: Estudo de etiologia / Estudo observacional Limite: Adulto / Humanos / Masculino Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2004 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sêmen / Hormônios Esteroides Gonadais / Estudos de Casos e Controles / Química / Bandeamento Cromossômico / Cromossomos Humanos Y / Fator de Crescimento Epidérmico / Alfa-Glucosidases / Azoospermia / Genética Tipo de estudo: Estudo de etiologia / Estudo observacional Limite: Adulto / Humanos / Masculino Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2004 Tipo de documento: Artigo