Treatment and prognosis of solid pseudopapillary neoplasms with metastases or recurrence / 中华外科杂志
Chinese Journal of Surgery
;
(12): 685-689, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-308499
ABSTRACT
<p><b>OBJECTIVE</b>To describe the treatment and prognosis of solid pseudopapillary neoplasms (SPN) with metastases or recurrence.</p><p><b>METHODS</b>The clinical date of 24 patients with histological confirmed SPN with metastases or recurrence from January 2000 to April 2014 were retrospectively analyzed. There were 22 females and 2 males, with mean age of (36 ± 16) years. Fourteen patients had local recurrence or metastasis after surgery, with a mean time of recurrence (44 ± 29) months. Ten patients were defined SPN with distant metastasis at first admission. Nineteen patients underwent surgical resection, among them, 11 patients received complete resection. Nine cases underwent chemotherapy. Kaplan-Meier method was used to identify prognostic factors.</p><p><b>RESULTS</b>Twenty-four patients were followed-up, 9 patients died. Median survival time was 47 months, and 1-year, 3-year, and 5-year survival was 91.7%, 65.1%, 49.6%, respectively. Age (χ(2) = 6.858, P = 0.009), primary tumor diameter (χ(2) = 4.322, P = 0.038), extrahepatic metastasis (χ(2) = 5.279, P = 0.022) and complete resection of metastases and recurrence (χ(2) = 4.666, P = 0.031) were important prognostic factors for survival (P < 0.05).</p><p><b>CONCLUSIONS</b>For SPN with metastases or recurrence, good prognosis can also obtain after complete resection. Age, primary tumor diameter, extrahepatic metastasis and complete resection of metastases and recurrence are influence factors on prognosis of patients.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Pancreáticas
/
Patologia
/
Prognóstico
/
Cirurgia Geral
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Protocolos de Quimioterapia Combinada Antineoplásica
/
Taxa de Sobrevida
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Estudos Retrospectivos
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Terapia Combinada
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Metástase Neoplásica
/
Recidiva Local de Neoplasia
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Surgery
Ano de publicação:
2015
Tipo de documento:
Artigo
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